无机物的吸收、分配、代谢和排除以及毒性（ADM EöT ox）研究在药物和毒物研究中非常重要。近年来发展的在细胞层次上应用高通量和计算机等技术系统探索药物先导化合物的ADM EöT ox 发展迅速。金属和其它无机化合物的ADM EöT ox 研究在国内外都还是一个新兴的、具有广阔发展前途的跨学科研究领域。本文综述了国内外对于铁和铜以及稀土等金属的化合物的ADM EöT ox 研究结果。提出一些应该开展的工作和有待解决的问题

2003年度的诺贝尔化学奖授予洛克菲勒大学的Roderick MacKinnon博士和约翰斯·霍普金斯大学的Peter Agre博士，以表彰他们在细胞膜水分子通道和离子通道方面所做的开创性工作。本文简介2003年诺贝尔化学奖获得者及其工作。

探讨与生命科学相关专业的化学基础课程为适应新形势的发展需要应该进行的调整与改革。

Lanthanum ion (La3+) has been reported to affect proliferation or apoptosis of different cells. In the present study, La3+ was confirmed to promote both proliferation and apoptosis of NIH 3T3 cells at the same concentrations. La3+ was shown to promote proliferation by helping the cells to pass through the G1/S restriction point and enter S phase, however, the proliferating cells induced by incubation with La3+ eventually underwent apoptosis. The proliferation and apoptosis of NIH 3T3 cells induced by La3+ were well correlated with cell-cycle alterations. La3+ caused the phosphorylation of extracellular signal-regulated kinase (ERK) 1/2; while inhibition of ERK phosphorylation by 2'-amino-3'-methoxyflavone (PD98059) suppressed both proliferation and apoptosis induced by La3+. Based on the above experimental results, we postulated that La3+-promoted proliferation of NIH 3T3 cells could be interconnected with the cell apoptosis, possibly through cell-cycle machinery. Our results thus support the recent hypothesis that proliferation and apoptosis of cell are intrinsically coordinated.