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【期刊论文】Ananosic Acids B and C, Two New 18 (13f12)-abeo-Lanostane Triterpenoids from Kadsura ananosma
陈业高, Ye-Gao Chen, †, Li-Na Hai, ‡, Xin-Rong Liao, Guo-Wei Qin, §, Yu-Yuan Xie, and Fathi Halaweish*, ┴
J. Nat. Prod. 2004, 67, 875-877,-0001,():
-1年11月30日
Two new 18(13→12)-abeo-lanostane triterpenoid acids, ananosic acids B (1) and C (2), were isolated from the stems of Kadsura anaosma. Their structures were elucidated by spectral studies and chemical transformation. Compounds 1 and 2 were evaluated for cytotoxicity using CCRF-CEM leukemia cells and HeLa cells.
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【期刊论文】DIBENZOCYCLOOCTADIENE LIGNANS FROM KADSURA ANGUSTIFOLIA
陈业高, YE-GAO CHEN, PING WANG, ZHONG-WEN LIN†, HAN-DONG SUX, †, GUO-WEI OIN*, and YC-YUAN XIE
Phytochemistry, Vol. 48, No.6. pp. 1059-1062, 1998,-0001,():
-1年11月30日
Three new dibenzocylooctadiene lignans, named angustifolin A, B and C, were isolated from the stems of Kadsura angustifolia. Their structures and stereochemistries were elucidated by spectral studies.
Kadsura angustifolia, Schisandraceae, dibenzocyclooctadie lignan, angustifolin A,, B and C.,
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【期刊论文】New Iridoid Triesters form Valeriana jatamansi
陈业高, by Lili Yua), Rong Huangb), Changri Hanc), Yuping Lva), Yong Zhaoa), and Yegao Chen*a)
HELVETICA CHIMICA ACTA-Vol. 88 (2005),-0001,():
-1年11月30日
A considerable number of studies have been performed on plants of the Valeriana genus in the family of Valerianaceae. These investigations have yielded iriodoids, sesquiterpenoids, lignans, and alkaloids with pharmacological properties, including sedative, cytotoxic, antitumor, antionxidant, and vasorelaxant activities [1-5]. Valeriana jatamansi JONES, an annual herd distributed in the southwestern area of the people's Republic of China, was known in Chinese folk medicine to have tranquilizing hypnotic and antiviralactivities [6-8]. Previous chemical investigation of V. jatamansi revealed the presence of iriodoids, sesquiterpenoids, and an essential oil [2] [6] [8]. Further investigation of the roots of this plant led now to the isolation of two new iridoid triesters, valeriotriates A (1) and B (2). It is noteworthy that few naturally occurring 6-hydroxy-substituted iridoids were foud in the plants of the genus Valeriana. We herein report the isolation and characterization of 1 and 2.
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【期刊论文】LIGNANS FROM KADSURA ANGUSTIFOLIA
陈业高, Ye-Gao Chen, Guo-Wei Qin*, and Yu-Yuan, Xie Kin-Fai Cheng*, Zhong-Wen Lin, and Han-Dong Sun, Young-Hwa Kang, and Byung-Hoon Han
Published on Journal of Asian Natural Products Research, 1998, 1 (2): 125,-0001,():
-1年11月30日
A new dibenzocyclooctadiene lignan named angustifolin D (1) together with four known lignans: kadsulignan L (2), kadsulignan N (3), schisantherin P (4) and meso-dihydroguaiaretic acid (5) were isolated from the stems of Kadsura angustifolia. Their structures and stereochemistries were elucidated by spectral studies. Compounds 2 and 5 showed moderate platelet-activating factor (PAF) antagonistic activities with IC50 values of 2.6
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陈业高, Ye-Gao Chena, *, Zheng-Cai Wub, Shi-Hong Guia, Yu-Ping Lva, Xin-Rong Liaob, Fathi Halaweishc
Fitoterapia 76(2005)370-373,-0001,():
-1年11月30日
The lignans, gomisin G (1), schisantherin A (2), benzoylgomisin Q (3) and isoanwulignan (4) were isolated from the stems of Schisandra henryi. Compound 1 showed moderate DNA strand scission activity and significant cytotoxic effect on leukemia and Hela cells in vitro. Compound 1 represents a new type of DNA strand scission agent.
Schisandra henryi, Lignans, Cytotoxic activity
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