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2007年04月04日

【期刊论文】Preparation and Characterization of Natural Hydroxyapatite from Animal Hard Tissues

吕晓迎, L

Key Engineering Materials Vols. 342-343 (2007) pp. 213-216,-0001,():

-1年11月30日

摘要

The purpose of this study is to find out an effective method to prepare natural hydroxyapatite (HA) from biological source, i.e., pig bones, pig teeth, and extracted human teeth. For the preparation of natural HA a calcining method with different temperatures was used, in combination with the thermal gravimetric analysis (TGA). Three analysis methods, i.e., Fourier transform infrared spectroscope (FTIR), X-ray diffraction (XRD), and inductively coupled plasma (ICP) have been used to investigate the characteristics of the prepared materials. The spectrum of the prepared material, obtained by means of FTIR and XRD, are consistent with the standard FTIR spectrum and JCPDS index of XRD of hydroxyapitite. It confirms that the material prepared is hydroxyapitite indeed. The natural HA obtained by calcining at 850℃ shows a desired quality.

Natural HA, Pig bone and pig teeth, Calcinations, FTIR, XRD, ICP

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2007年04月04日

【期刊论文】Fully Integrated and Low Power CMOS Amplifier for Neural Signal Recording

吕晓迎, Yufeng Wang, Zhigong Wang, Xiaoying L

Proceedings of the 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference Shanghai, China, September 1-4, 2005,-0001,():

-1年11月30日

摘要

This paper presents a fully integrated and low power CMOS amplifier for neural signal recording. It consists of a band-filtering preamp and a current-mode instrumentation amplifier. The design approach and the noise optimizing are briefly discussed. A 0.6

Neural signal recording, neural prosthesis, CMOS, ENG

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2007年04月04日

【期刊论文】表面等离激元共振( SPR)生物传感器对聚氨酯材料血浆蛋白吸附的实时原位动态研究

吕晓迎, 黄炎, 唐祖明, 洪庆月, 陆祖宏, 钟银屏, 叶卫华, 刘凌云

中国生物医学工程学报2003年4月第22卷第2期/CHINESE JOURNAL OF BIOMEDICAL ENGINEERING April 2003, Vol. 22, No.2,-0001,():

-1年11月30日

摘要

应用实验室自行研制的自动扫描式表面激元共振(SPR)生物传感器对三种聚氨酯材料进行了血液蛋白质吸附实验,以传感片上的金膜作为对照材料。同时应用原子力显微镜对金膜和聚氨酯材料的超微结构与材料表面上所吸附的蛋白质进行了表征。实验结果显示,四种材料对纤维蛋白原和IgG的吸附量顺序均为:金膜 > H50-0 > H50-50 > H50-100。T-检验结果表明,金膜对纤维蛋白原和IgG吸附量与三种聚氨酯材料均有显著差别。该结果表明聚氨酯材料的血液相容性明显好于金膜对照材料。

表面激元共振传感器, 原子力显微镜, 蛋白质吸附, 聚氨酯, 金膜

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2007年04月04日

【期刊论文】BioStarM - 140s芯片基因信息查询系统的构建及应用

吕晓迎, 陆慧琴, 包翔, 马慧敏

东南大学学报(自然科学版)2006年7月第36卷第4期/JOURNAL OF SOUTHEAST UNIVERSITY (Natural Science Edition) July. 2006, Vol. 36, No. 4,-0001,():

-1年11月30日

摘要

应用生物信息学数据库查询的方法,对BioStarM - 140s小鼠基因表达芯片上的14112个基因进行相应注释信息的查询和所对应蛋白质功能的分类。首先参照人类综合型芯片上基因的功能分类,设定了14个蛋白质类别,然后采用Visual C++编程语言,构建了基因信息查询系统。应用该查询系统,进行了网络生物学数据库信息资源的自动直接查询,共搜索到有注释信息的基因12070个;进一步按照所设定的14个蛋白质类别对12070个基因进行分类查询,搜索到了与这14个分类相符合的、具有详细蛋白质功能注释信息的基因共 1606个。

生物信息学, 数据库查询, 基因表达芯片

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2007年04月04日

【期刊论文】Study of Protein Adsorption on Biomaterial Surfaces by SPR

吕晓迎, He Jian, L

Key Engineering Materials Vols. 342-343 (2007) pp. 825-828,-0001,():

-1年11月30日

摘要

Object: The aim of this study was to set up a SPR sensor and to investigate protein adsorption onto biomaterial surface using it. Methods: The adsorption of human albumin (Alb), fibrinogen (Fib) and immunoglobulin G (IgG) onto polyurethane (PU) H50-50 and Au surface were measured using this SPR sensor. Results: The results of protein adsorption showed that the amount of Alb, Fib and IgG adsorbed on PU (H50-50) are smaller than Au, and on these two material surfaces, the amount sequence of adsorbed protein is: IgG> Fib > Alb. Both the Alb/Fib ratio and Alb/IgG ratio on PU (H50-50) surface are higher than Au. Conclusion: The antithrombogenicity of PU (H50-50) is better than Au.

Surface plasmon resonance, Biosensor, Protein adsorption, Biocompatibility

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    东南大学,江苏

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