Object: The aim of this study was to set up a SPR sensor and to investigate protein adsorption onto biomaterial surface using it. Methods: The adsorption of human albumin (Alb), fibrinogen (Fib) and immunoglobulin G (IgG) onto polyurethane (PU) H50-50 and Au surface were measured using this SPR sensor. Results: The results of protein adsorption showed that the amount of Alb, Fib and IgG adsorbed on PU (H50-50) are smaller than Au, and on these two material surfaces, the amount sequence of adsorbed protein is: IgG> Fib > Alb. Both the Alb/Fib ratio and Alb/IgG ratio on PU (H50-50) surface are higher than Au. Conclusion: The antithrombogenicity of PU (H50-50) is better than Au.

介绍了一种牙科材料细胞毒性评定的新方法—MTT试验法。该比色法以MTT四唑为基质，只测定体外存活的细胞数量，具有快速、简便、灵敏等优点。其指标客观且能定量分析，显示了与其他细胞毒性测定方法良好的相关性。作者依据自己的经验，强调了建立细胞生长代谢标准曲线的必要性。

The state-of-art of the pick-up, the process and the regeneration of central neural signals by means of microelectronic techniques are reviewed. The in-detail discussed topics include the electrodes for neural signal pick-up and for the function electrical stimulation (FES) of neurons, the integrated circuits (IC) for the neural signal process and for the FES-signal generation, the energy supply and the low-power design of the ICs, as well as the biocompatibility test and the micro operation of the whole system implanted in-body.

The quantity and secondary structure of adsorbed albumin (Alb) and immunoglobulin G (IgG) on two kinds of biomaterial surfaces-polyurethane (PU (H50-50)) and polystyrene (PS) were studied using Fourier transform infrared spectroscopy (FTIR). The original spectra tested by FTIR were processed using second-derivation and self-deconvolution techniques to obtain the content of different secondary structures of adsorbed proteins, which could be used to evaluate the denatured degree of proteins. Results showed that the quantity of Alb adsorbed on PU (H50-50) surface is larger than PS. The hydrophobic features of material played a role in conformational change of adsorbed protein, and indicated that the denatured degree caused by hydrophobic PS was greater than hydrophilic PU (H50-50). The blood compatibility of PU (H50-50) was likely to be better than PS.