应用实验室自行研制的自动扫描式表面激元共振(SPR)生物传感器对三种聚氨酯材料进行了血液蛋白质吸附实验，以传感片上的金膜作为对照材料。同时应用原子力显微镜对金膜和聚氨酯材料的超微结构与材料表面上所吸附的蛋白质进行了表征。实验结果显示，四种材料对纤维蛋白原和IgG的吸附量顺序均为：金膜 > H50-0 > H50-50 > H50-100。T-检验结果表明，金膜对纤维蛋白原和IgG吸附量与三种聚氨酯材料均有显著差别。该结果表明聚氨酯材料的血液相容性明显好于金膜对照材料。

介绍了一种牙科材料细胞毒性评定的新方法—MTT试验法。该比色法以MTT四唑为基质，只测定体外存活的细胞数量，具有快速、简便、灵敏等优点。其指标客观且能定量分析，显示了与其他细胞毒性测定方法良好的相关性。作者依据自己的经验，强调了建立细胞生长代谢标准曲线的必要性。

目的 　评价牙科复合树脂材料的抗磨损性。方法 　应用程控多功能口腔模拟机和三维图像激光测试仪对4种牙科复合树脂进行抗磨损性的实验研究。结果 　材料磨损坑体积大小的顺序为：牙釉质 < Targis Dentin < Dentacolor < Artglass < Vita Zeta。磨损坑最深点大小的顺序为：牙釉质 < Targis Dentin < Artglass < Dentacolor < Vita Zeta。 结论 　Targis Dentin的抗磨损性接近于牙釉质，其他3种材料的抗磨损性明显较牙釉质差。新型体外实验系统具有快速、准确、经济、高效的特点。

Object: The aim of this study was to set up a SPR sensor and to investigate protein adsorption onto biomaterial surface using it. Methods: The adsorption of human albumin (Alb), fibrinogen (Fib) and immunoglobulin G (IgG) onto polyurethane (PU) H50-50 and Au surface were measured using this SPR sensor. Results: The results of protein adsorption showed that the amount of Alb, Fib and IgG adsorbed on PU (H50-50) are smaller than Au, and on these two material surfaces, the amount sequence of adsorbed protein is: IgG> Fib > Alb. Both the Alb/Fib ratio and Alb/IgG ratio on PU (H50-50) surface are higher than Au. Conclusion: The antithrombogenicity of PU (H50-50) is better than Au.

The aim of present work was to study the interaction between human plasma protein-albumin (Alb) and immunoglobulin G (IgG) and the surfaces of two kinds of diamond-like Carbon (DLC-A and DLC-B) and titanium (Ti) film. Fourier transform infrared spectroscopy (FTIR) was used to perform both quantity investigation and secondary structure analysis of above two proteins adsorbed on material surfaces. A modified Coomassie brilliant blue (CBB) protein assay was also used to study the amount of adsorbed proteins. The result of FTIR quantitative evaluation shows that the ratio of adsorbed Alb to IgG (RA/I) on three kinds of material surface has an order: DLC-A > DLC-B > Ti, which is coincide with the result from CBB protein assay. The result of secondary structure analysis shows that the conformation of Alb and IgG changes in a largest degree after adsorbed on Ti and a smallest degree on DLC-A surface. Both the results indicate that the anti-thrombogenicity of DLC-A seems to be the best and Ti is the worst.